Traffic management is handling a stretch of State Highway 4 following a crash involving two trucks.
A stop/go system is in place in Kakatahi and motorists are advised to take extra care.
Police were alerted to the incident around 9.10am.
A police spokeswoman said there are no reported injuries and a specialist tow truck was required.
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State Highway 4, from Whanganui River Rd to Fields Track, was fully closed until 1.20pm.