"Increased traffic volumes, tiredness and driving in unfamiliar environments can make driving over these long weekends more stressful," Mr D'Ath said.
"Remember you're sharing the road with many others, you have a responsibility to be courteous and patient to ensure you look after yourself, your families and other road users."
Drivers can find more personalised information about driving conditions on their frequently used routes, by signing up to On The Move at www.onthemove.govt.nz.
For real-time information on highway conditions and incidents or to report issues on the network visit www.nzta.govt.nz, call 0800 4 HIGHWAYS.
NZ Transport Agency's top tips for a safe Labour Day Weekend
*Allow plenty of time, make your journey part of the holiday.
*Rest stops are important for the driver and passengers.
*If possible, share the driving.
*Wear your seatbelt and check your passengers are belted up after every break.
*Keep left of the centreline.
*Take extreme care if overtaking, ensure you have plenty of room to pass safely. If cars are backed up behind you, pull over at a safe spot and relieve the pressure. If you are following a slower vehicle, give it room and keep everyone's stress levels down.
*Maintain a three-second gap when following vehicles in front
*Check your vehicle is safe - tyres/spare tyre, indicators, windshield wipers, lights - before you head away.