A mas has died in his cinema seat while watching a horror film's most frightening scene.

The 65-year-old was watching The Conjuring 2 with a friend at a movie theatre in Tiruvannamalai, a town in the Indian state of Tamil Nadu, on Thursday night.

According to the Times of India, police said once the film about the "Enfield haunting" in the 1970s reached one of the scariest parts, the man began having chest pains and fainted. He was taken to hospital but had already died.

In an even more bizarre twist, the man's dead body has now gone missing. Hospital staff asked the man's friend to take the body to a medical college for a post-mortem, but he's since disappeared with the body.

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The cause of death remains unknown, but many believers in paranormal activity think it was linked to the movie.

The Conjuring 2 is based on the "Enfield haunting" of 1977 to 1978.

Janet and Margaret Hodgson were two sisters at the centre of the horrifying story of paranormal activity.

Photos taken in the middle night appeared to show Janet, then aged 11, levitating above her bed. The sisters maintain that they were terrorised by a poltergeist, and recently returned to the house where the haunting was said to take place.

During a behind-the-scenes interview to promote The Conjuring 2, Janet recalled some of her terrifying experiences.

"My brother and I were laying in bed and we were chatting like we normally did. We turned the light out and settled down to go to sleep and we could hear this shuffling noise near the bedroom door," she said.

Frances O'Connor, Madison Wolfe and Lauren Esposito in a scene from the cinema thriller The Conjuring 2. Photo / AP
Frances O'Connor, Madison Wolfe and Lauren Esposito in a scene from the cinema thriller The Conjuring 2. Photo / AP

"The chest of drawers started shuffling and moved towards the door and me and my brother Johnny sat up and we were really frightened.

"Mum came in and turned the light on and said 'what's all this noise about' and we said 'Mum, Mum, the chest of drawers is moving towards the doorway'."

"She pushed it back and then it started to shuffle out again and she couldn't push it back."

Janet said that on one occasion a curtain wrapped itself around her neck.

About a week ago, a man said he'd had an eerie experience after watching The Conjuring 2.

Damian Ng Yih Leong and a friend returned to their hotel room at about 2.30am after watching the movie in Miri, a city in Malaysia.

His friend brushed her teeth, then emerged from the bathroom and asked if Mr Leong had pranked her by drawing a cross on the mirror in the toilet.

"I was puzzled, as I was resting on the bed all the while and I thought she was trying to prank me," he wrote on Facebook.

"We then realised that we were not pulling pranks at each other. I then went to the toilet to check out the cross ... It was freshly drawn, as I could see water creeping down on one side of the cross, and the stain is still fresh.

"I then asked her how that could be me when she was the one standing in front of the mirror all the time."

Mr Leong then asked to change hotel rooms.

"This is my first encounter with paranormal activity and it was certainly hair raising for us," he said.