A knifeman has killed at least 19 people and injured 45 in Japan, according to local reports.

The attacker went into a centre for disabled people in Sagamihara, outside of Tokyo, brandishing a knife.

Police were called to the scene at around 2.30am local time after residents saw a man armed with a knife in the grounds of the Tsukui Yamayuri Garden.

Asahi Shimbun reported that the suspect was quoted by police as saying "I want to get rid of the disabled from this world."

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