"To families, friends, neighbours, loved ones, and all those caught up in the painful process of recovery, let us say to them: our admiration for you is unconditional; for the fortitude and resilience you have shown, for your determination never to give up.
"You have shown that terrorist acts cannot crush the human spirit. That is why terrorism will never prevail. And even in the darkest moments of grief, it is possible to glimpse the flickering flame of hope."
The tragedy continued to forge a strong bond between Lockerbie Academy and Syracuse University [New York], he said.
"Syracuse lost 35 of its own on that fateful evening. Nothing can restore the promise of those young lives cut short."
Each year since the tragedy the university has awarded 35 scholarships to its own undergraduates and two to Lockerbie students.
"This is the lasting and optimistic legacy bequeathed to future generations on behalf of those who lost their lives on this day 25 years ago and whom we remember today," Cameron said. AAP