With a strong wind blowing over the shooting range from left to right, many athletes struggled.
Defending overall champion Tora Berger of Norway missed two targets but rallied to finish fourth, 6.4 seconds behind Gasparin. Berger went top of the sprint standings with 91 points, leading Russian pair Olga Zaitseva and Irina Starykh, who each have 88.
Two months before defending her Olympic sprint title, Anastasiya Kuzmina of Slovakia placed 13th, 41.2 seconds off the lead after two mistakes at stand shooting.
Gabriela Soukalova of Czech Republic finished 23rd after two misses but remained in the lead of the overall standings with 116 points, leading Zaitseva by four points.
A men's 10K sprint was scheduled later Friday.