Based on the medical records he had seen, Ms Nathan's condition was "irretrievable" with her cardiovascular, renal and central nervous systems all failing and her blood coagulating by the time she was rushed to Waikato Hospital.
He said the most likely cause was an amniotic fluid embolism (AFE) where some of the fluid in the amniotic sac around the baby leaks into the mother's bloodstream.
The fluid is highly toxic to the mother's blood and causes a number of adverse effects.
Earlier, the inquest heard a transcript of the 111 recordings taken on the day Ms Nathan died that revealed St John Ambulance staff's concerns about the young midwife's apparent lack of experience, with one saying "she had no idea what was going on".
The midwife, who has interim name suppression and spoke via a video link from the country where she now lives, met Ms Nathan in November 2011 and became her lead maternity carer with just a year's experience, having graduated with a bachelor of midwifery in November 2010. The inquest continues.