The event is to be held at Otumoetai College.
"I'm pumped to be able to jump into it. It's a cause that's close to everyone," said James.
James' mother suffered from breast cancer when he was a toddler, while Lauren's grandparent, and Courtney's older sister had passed away from cancer.
Courtney and Lauren have been training seven days a week for their college rowing team, so were keen to take up the challenge of rowing indoors for nearly six hours straight.
James has been approaching local businesses for sponsorship and prizes to be used in a raffle.
He said he had received about $500 worth of vouchers and goods already.
"It's just in my nature. I want to help out.
"You must be the change you want to see in the world."
The Year 10 students, all 14, plan to promote the event to their peers in assembly, with the help of head student, Josh Kingsford.
The public is invited to go to www.projectrowingchallenge.
co.nz for more information about the event, and to make donations.