The Chinese city where the coronavirus first emerged reported no new homegrown cases Thursday, while the death toll in Italy was poised to overtake China's in a stark illustration of how the outbreak has pivoted toward Europe and the US.
The damage to the world's largest economy kept piling up, with unemployment claims surging in the United States, while the virus appeared to be opening an alarming new front in Africa, where in less than three weeks it has spread to 35 countries.
The epidemic has also now reached at least one European head of state, 62-year-old Prince Albert II of the tiny principality of Monaco. The palace announced that he tested positive for the virus but was continuing to work from his office and was being treated by doctors from Princess Grace Hospital, named after his American actress mother.
In the US, Congress rushed to pass a US$1 trillion emergency package to shore up the sinking economy and help households pull through the crisis, with the first of two possible rounds of relief checks consisting of payments of US$1000 per adult and US$500 for each child.
The worldwide death toll crept toward 10,000 as the total number of infections topped 220,000, including nearly 85,000 people who have recovered.
French Prime Minister Edouard Philippe pleaded with people to keep their distance from one another to avoid spreading the virus, even as the crisis pushed them to seek comfort.
"When you love someone, you should avoid taking them in your arms," he said in Parliament. "It's counterintuitive, and it's painful. The psychological consequences, the way we are living, are very disturbing — but it's what we must do."
Italy, a country of 60 million, registered 2978 deaths Wednesday after 475 more people died. Italy was likely to overtake China's 3249 dead — in a land of 1.4 billion — upon the release of Thursday's figures.
The American death toll rose to 149, primarily elderly people.
Health authorities have cited a variety of reasons for Italy's high toll, key among them its large population of elderly people, who are particularly susceptible to serious complications from the virus, though severe cases have also been seen in younger patients. Italy has the world's second-oldest population, and the vast majority of its dead — 87 per cent — were over 70.
Jonas Schmidt-Chanasit, a virologist at Germany's Bernhard Nocht Institute for Tropical Medicine, said Italy's high death rate could be explained in part by the almost total breakdown of the health system in some areas.
"That's what happens when the health system collapses," he said.
On a visit to the northern city of Milan, the head of a Chinese Red Cross delegation helping advise Italy said he was shocked to see so many people walking around, using public transportation and eating out.
Sun Shuopeng said Wuhan saw infections peak only after a month of a strictly enforced lockdown.
"Right now we need to stop all economic activity and we need to stop the mobility of people," he said. "All people should be staying at home in quarantine."
Aside from the elderly and the sick, most people have mild or moderate symptoms, like a fever or cough, and most recover in a matter of weeks.
Spain has been the hardest-hit European country after Italy, and in Madrid a four-star hotel began operating as a makeshift hospital for coronavirus patients.
The director of the group that runs the Ayre GH Colon hotel tweeted: "365 rooms more to help win the war." The Madrid Hotel Business Association said it has placed 40 hotels with room for 9000 people at the service of the Madrid region, which has near half of Spain's 17,000 or so cases.
In London, home to almost 9 million, the government urged people to stay off public transportation as authorities considered imposing tougher travel restrictions.
The British supermarket chain Sainsbury's reserved the first hour of shopping for vulnerable customers, one of many such efforts around the world.
Jim Gibson, 72, of London, said he found most of his groceries there in a "relatively trauma-free" experience. But he fretted that he hadn't been able to get the medicine he needed for his wife and himself, and expressed concerns that Britain's government had been too slow in ramping up testing.
"You can't go on ignoring World Health Organisation guidelines — if they're wrong, who the hell is right?" he said. "Let's have no shilly-shallying."
The British government, which was slow to react to the virus, has shifted gears and is now drawing up legislation giving itself new powers to detain people and restrict gatherings. The bill is expected to be approved by Parliament next week.
Thursday marked the first time since January 20 that the Chinese city of Wuhan showed no new locally transmitted cases, a rare glimmer of hope and perhaps a lesson in the strict measures needed to contain the virus.
Wuhan, which has been under a strict lockdown since January, once was the place where thousands lay sick or dying in hurriedly constructed hospitals. But Chinese authorities said all 34 new cases recorded over the previous day had come from abroad.
"Today, we have seen the dawn after so many days of hard effort," said Jiao Yahui, a senior inspector at the National Health Commission.
Meanwhile, the World Health Organisation warned that the virus is spreading quickly in Africa — an especially alarming development, given the poor state of health care in many of its countries.
"About 10 days ago we had about five countries" with the virus, said WHO's Africa chief, Dr. Matshidiso Moeti. Now 35 of Africa's 54 countries have cases, with the total close to 650. It is an "extremely rapid evolution," she said. The first sub-Saharan Africa case was announced February 28.
European stock markets were up only slightly after losses in Asia despite a massive €750 billion stimulus package announced overnight by the European Central Bank.
Wall Street was calm in early trading by the standards of the past few days, when traders — weighing the increasing likelihood of a recession against the huge economic support pledged by global authorities — have caused wild swings.
With wide swaths of the US economy grinding to a halt, the number of Americans filing for unemployment benefits surged by 70,000 last week, more than economists expected.
The US Federal Reserve unveiled measures to support money-market funds and borrowing as investors worldwide rush to build up dollars and cash.
Ford, General Motors and Fiat Chrysler, along with Honda and Toyota, announced on Wednesday that they would close all of their factories in the US, Canada and Mexico. The shutdown of Detroit's Big Three alone will idle about 150,000 workers.
More borders closed, leaving tens of thousands of tourists wondering how they would get home. In the Pacific, Australia and New Zealand shut out tourists, while Fiji reported its first virus case, a worrying development in a region with poor healthcare.
Iran's Supreme Leader Ayatollah Ali Khamenei planned to pardon 10,000 more prisoners — including an unknown number of political detainees— to combat the virus. The country, where more than 1100 people have already died, previously freed 85,000 prisoners on temporary leave.
In Austria, the province of Tyrol put 279 municipalities under quarantine because of a large number of infections, barring people from leaving towns or villages except to go to work.