The mother of Dimitrous "Jimmy" Gargasoulas has expressed the disgust she feels for his shocking rampage through Melbourne's CBD on Friday.

Emily Gargasoulas said she is ashamed her son had "intentionally" ploughed his vehicle into pedestrians - leaving four people confirmed dead and 15 injured.

"I feel so ashamed and bad, you know," she told 7 News. "I don't want to be known that I'm the mother.

"Go to hell and die in hell."

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James 'Jimmy' Gargasoulas aka Dimitrious Gargasoulas. Photo / Facebook
James 'Jimmy' Gargasoulas aka Dimitrious Gargasoulas. Photo / Facebook

Ms Gargasoulas also spoke about the bloody fight between James and his younger brother, Angelo, on friday.

She said the fight, which saw Jimmy allegedly stab his brother in the face, was over Angelo's sexuality.

"Jimmy keeps saying to me, I'm going to kill all gays and poofters and lesbians," she said.

Source: TODAY

Gargasoulas' girlfriend, Akiir Muo, has also spoken of the horror, saying she was held hostage by her partner during his wild crime spree.

"He was driving really erratically ... he kept saying it was the end of the world and how he planned to run over people in the city because the police were following us," she told the Herald Sun.

Pedestrians running for their lives from an out of control vehicle in Melbourne narrowly escaped death by diving into a convenience store. Twitter/@sunprawn

"When I found out he actually killed people I just went into shock. I started crying and thought, "Jimmy what have you done"."

James Gargasoulas remains under guard in hospital after he was shot in the arm by police.