Gaza's last tiger left the war-ravaged Palestinian enclave with monkeys, emus, a porcupine and other animals from a zoo dubbed the "world's worst", heading for a new life in South Africa and elsewhere.
Laziz (Cutey in Arabic) the tiger and the 15 other remaining animals from the Khan Younis zoo were driven on a trailer in cages to the Erez crossing before dawn local time, an AFP journalist said.
The animals crossed the border en route to sanctuaries and zoos in South Africa, Jordan and Israel for "a better quality of life", the Israeli Army said.
As well as Laziz, five monkeys, two emus, two deer, two eagles, two turtles, a pelican and a porcupine were transferred, the Four Paws charity ensuring the animals' welfare said.
For months vets from Four Paws had been visiting the zoo in southern Gaza to treat the animals and transfer them out after international outcry at photos of their conditions.
Dozens of animals had died in the zoo, some of starvation, and badly stuffed bodies of dead crocodiles, lions and others were left in the open, surrounded by piles of bones.
The NGO says on its website that Khan Younis had "been known as the 'worst zoo in the world' since it became public last year that the zoo was crudely mummifying the animals that died in their care and displaying them."
The transfer leaves the zoo empty and it will now be closed.
"So many people have followed the progress of our mission eagerly and shown their solidarity with Laziz and the other animals," Four Paws vet Amir Khalil said in a statement.
"We are happy that we were finally able to close down Khan Younis zoo."
Laziz's case attracted particular attention, after it was revealed the near-starving tiger had originally been brought to Gaza from Senegal via Egypt, where he was smuggled through tunnels into the enclave.
He will now be transferred to the Lionsrock refuge for big cats in South Africa.
"We were quite worried if Laziz would go into his transport crate without any issues," Khalil said.
"But the tiger just went straight into the box as if he knew that we will bring him to a nice home."
In the years after its 2007 opening there were more than 100 animals housed at the zoo, but they were decimated by repeated wars and shortages of customers.
The owners were unable to afford enough food, with some animals starving.
"I am very sad," lamented owner Ziad Aweda. "I brought these animals from Libya, Sudan, Egypt and even South Africa to Gaza."
The nearly two million residents of Gaza are also suffering and find it difficult to get permits to travel to Israel, which has maintained a blockade on the enclave for a decade.
More than two-thirds of Gazans are reliant on some form of aid, according to the United Nations.
Hamas, which runs Gaza, has fought three wars with Israel since 2008, the most recent in 2014 in which 2251 Palestinians died, the majority civilians, according to the United Nations.
Seventy-three Israelis, including 67 soldiers, were also killed.
The Israeli blockade of the enclave and Egypt's closed border have suffocated the economy, making it increasingly hard for Gazans to find money for leisure.