An amateur Mexican footballer is on the run after allegedly head-butting and inadvertently killing a referee who gave him a red card.

During his protestations, Vazquez head-butted referee Victor Trejo, who then fainted.

Paramedics on site tried to revive the victim to no avail, and the alleged perpetrator fled in a pick-up truck after seeing the ref had suffered serious injury.

According to emergency services on the scene, the referee died of a "widespread subarachnoid hematoma," caused by a blow to the head.

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Police in Mexico are still on the lookout for the alleged killer.