Top seed Novak Djokovic has continued his domination of men's tennis with a 6-3 6-3 victory over Japan's Kei Nishikori in the final of the Miami Open in Florida.



Djokovic dropped serve in the first game on Sunday but it was pretty much one-way traffic after that as he outclassed the sixth seed in all facets of the game on the hardcourt at Key Biscayne.



The 28-year-old Serb took 85 minutes to join American Andre Agassi as a six-time Miami Open winner, for his 63rd career title.



He claimed $US1,028,300 ($A1.34 million), becoming the sport's all-time leading money-winner with career earnings approaching $US100 million.

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It is his fourth consecutive championship, and his 28th overall, in the Masters 1000, a series of nine tournaments considered the most prestigious other than the four grand slams.



It is also Djokovic's fourth title of 2016, following victories at the Australian Open, Qatar and Indian Wells.



His only blemish on an otherwise perfect record so far this year came in Dubai in February, when he retired during a quarterfinal with an eye infection.