A pedestrian has been seriously injured after being hit by a car in Southland.

Emergency services are at the scene of the crash, on State Highway 6, the Lumsden to Dipton Highway, around 8km south of Lumsden.

It appeared a car had hit the male pedestrian, Southern District Command Centre Senior Sergeant Brian Benn said.

A helicopter is flying the injured man to hospital.

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The road has been closed and motorists can expect delays.

Police will investigate the crash.