Sharon Osbourne underwent extensive DNA tests with her husband Ozzy to uncover their genetic propensity for disease.
The 60-year-old television personality and wife of the Black Sabbath rocker is a colon cancer survivor and the malignancy has been in remission for about a decade.
Sharon and Ozzy took comprehensive tests on their genetic code worth US$250,000 (A$238,540) at the request of researchers.
"The scientist wanted to see how Ozzy had lived so long despite the drink and drugs. I said he would do it and they said: 'We are doing you too'," she revealed on Howard Stern's radio show.
"The tests tell you all your genes and what you might get or have got.
"My husband walks away and he is genetically blessed and is perfect, thank God. But I had colon, breast and ovarian cancer genes."
Sharon had a double mastectomy to prevent breast cancer.
She is happy with the results of her restoration surgery.
"I had my entire breasts cut off and they rebuilt them," Sharon said.
"They look very small and perky, like they belong on somebody else but me. I have only got one nipple but I am going to have the other done."