People involved in a crash on State Highway 2, south of Waihi, have been treated for minor injuries.
A Northern Fire Service Communications spokesman said the collision, which happened about 11.50am, involved a heavy truck and trailer unit and a van.
Both vehicles are off the road, 500m north of Bridgeman Lane.
The spokesman said it was understood the patients suffered minor injuries and had been treated by St John ambulance staff.
It was unclear whether the road has been blocked.
A police spokesperson said police were on their way.