Kiwis are betting on the All Blacks annihilating the USA Eagles this weekend.
The odds of an American upset are at 51:1.
The TAB is not taking head-to-head bets on the All Blacks; but anyone willing to believe the Americans will surprise the world champions will be in for a big payout.
TAB spokesman Glen Saville said an All Blacks win was "a sure thing".
"We will take head-to-head bets on the USA Eagles, with a win for them paying $51 to the dollar," he said.
Watch: Rugby: All Blacks arrive in USA
"But the majority of the money is going on the 57.5 points start for the All Blacks - effectively, they're betting that the All Blacks will thrash the USA Eagles by 58 points or more, paying $1.87."
Mr Saville said what was particularly interesting was where bets would go once the starting squads were announced this week.
"Although we can't open a book on it, we're predicting the return of Sonny Bill Williams straight into the starting side - but we're less sure of how many tries he'll score.
"We'll be letting punters decide with a special book on SBW's try-scoring abilities for this match."
Former All Blacks Eric Rush and Michael Jones are understood to be taking part in events leading up to the match, and Indycar driver Scott Dixon and American actress Jessica Pimentel are among celebrities attending the game. Kiwi opera sensation Sol3 Mio will sing the New Zealand national anthem, joining local opera singer Jim Cornelison, who will perform The Star-Spangled Banner.
Five things about Chicago
1. Founded in 1833.
2. Known as "The Windy City.
3. "Third biggest city in the US, population: 2.6 million people.
4. Soldier Field stadium, where the game will be held, is the home of the Chicago Bears American football team. It is the oldest NFL stadium, having opened in 1924, and has hosted rock concerts, stock car races, rodeos and circuses.
5. Ethnic make-up: 45% white, 33% black, 13% other, 5% Asian.